November 2022 – Page 2

November 30, 2022

Conagen develops high-purity non-GMO sulforaphane by bioconversion

Commercial production is underway for 2023.

Bedford, Mass., Nov. 29, 2022 (GLOBE NEWSWIRE) — Expanding on its portfolio of innovative nutritional products through biotechnology, Conagen, announced the development of its 99% high-purity sulforaphane. Made by a proprietary bioconversion technology, the company plans to begin the commercialization path in 2023. Conagen’s bioconversion methods enable the production of sustainable products from many naturally occurring compounds regardless of rarity or small quantities occurring in nature.

“As a supplement product, Conagen’s high-purity sulforaphane is appealing to consumers as the levels found in raw vegetables are too low to realize many of its promising health benefits,” said Casey Lippmeier, Ph.D., senior vice president of innovation. “We’re looking forward to expanding the nutritional market by commercializing sulforaphane in 2023.”

Sulforaphane has been associated with supporting health benefits against cancer, diabetes, digestion, and heart disease and promoting cognition. With biotechnology and biomanufacturing advancements, much like Conagen’s bioconversion technology, more nutritional offerings are produced at a high-quality and global scale.

Sulforaphane is found in cruciferous vegetables such as arugula, bok choy, broccoli, Brussels sprouts, cabbage, kale, radish, and more. In these vegetables, the inactive form of glucoraphanin belongs to the glucosinolate family of plant compounds. The sulfur-rich sulforaphane is activated only when vegetables are chewed or chopped to release myrosinase, a class of enzymes that play a role in the defense response of plants.

“Through Conagen’s bioconversion technology, we’re uncovering the great potential in sulforaphane as a powerful active health ingredient for consumers who are personalizing nutrition to support health functions,” said Lippmeier. “We can make safe and high-quality nutritional ingredients from natural sources and offer it at a global-scale cost-competitively so that brands may pass on the good health and savings to their consumers.”

Conagen’s sulforaphane is ideal for non-GMO supplement solutions to formulate products with a sustainable and natural consumer appeal. More research is emerging for understanding the optimistic effects on multiple health functions. As one example of many, biotechnology and biomanufacturing will continue to harness the power of biology and nature to develop and deliver solutions for better nutrition, health, and wellness. Conagen is expanding its sustainable, nutritional products portfolio to better humankind and the planet.

About Conagen
Conagen is making the impossible possible. Our scientists and engineers use modern synthetic biology tools to program micro-organisms and enzymes on a molecular level to produce high-quality, sustainable, natural products manufactured worldwide via precision fermentation and bioconversion. We focus on the bioproduction of high-value ingredients for food, nutrition, flavors and fragrances, pharmaceuticals, and renewable materials.

Attachments

Ana Arakelian, Head of Public Relations and Communications
Conagen
+1-781-271-1588
ana.arakelian@conagen.com

GlobeNewswire Distribution ID 8705501

November 30, 2022

Amazon Deforestation in Brazil Remains Near 15-Year High

Deforestation in the Brazilian Amazon slowed slightly last year, a year after setting a 15-year high, according to closely watched numbers published Wednesday. The data was released by the National Institute for Space Research.

The agency’s Prodes monitoring system shows the rainforest lost an area roughly the size of Qatar, about 11,600 square kilometers in the 12 months from August 2021 to July 2022.

That is down 11% compared with the previous year, when more than 13,000 square kilometers were destroyed.

For more than a decade deforestation in the Brazilian Amazon declined dramatically and never rose back above 10,000 square kilometers. Then came the presidency of far-right President Jair Bolsonaro, beginning in January 2019.

This will be the last report published under Bolsonaro, who lost his reelection bid and will leave office January 1. But part of the destruction that took place on his watch will not appear until next year, including the key months from August to October 2022. A because it is the dry season.

An analysis of the new yearly data from Climate Observatory, a network of environmental groups, shows that in the four years of Bolsonaro’s leadership, deforestation rose 60% over the previous four years. That is the largest percentage rise under a presidency since satellite monitoring began in 1998.

In one state, Para, a fierce rate of destruction fell by 21% yet it was still the center of one-third of all Brazil’s Amazon forest loss. Part of the tree cutting and burning happens in areas that are ostensibly protected. One such area is Paru State Forest, where the nonprofit Amazon Institute of People and the Environment registered 2 square kilometers of deforestation in just October.

“In recent years, deforestation has reached protected areas where previously there was almost no destruction,” Jacqueline Pereira, a researcher with the Amazon Institute, told The Associated Press. “In Paru’s region, the destruction is driven by lease of land for soybean crops and cattle.”

Another critical area is the southern part of the state of Amazonas, the only state that increased deforestation in the most recent data, by 13% compared to the year before. It’s largely attributable to Bolsonaro’s push to pave about 400 kilometers of the only road that connects Manaus, home to 2.2 million people, with Brazil’s larger urban centers further south. Most Amazon deforestation occurs alongside roads where access is easier and land value is higher.

Researchers and environmentalists have blamed Bolsonaro’s policies for the surge in deforestation. The administration weakened environmental agencies and backed legislative measures to loosen land protections in the name of economic development, paired with a view of occupying a sparsely populated territory at any cost. This policy has emboldened land robbers and spurred more illegal mining.

Bolsonaro’s successor, leftist former President Luiz Inácio Lula da Silva, promised cheering crowds at the recent U.N. climate conference in Egypt to end all deforestation in the country by 2030.

“There will be no climate security if the Amazon isn’t protected,” he said.

The last time da Silva was president, from 2003 to 2010, deforestation fell sharply. On the other hand, he backed initiatives that set in motion destruction in the long run, such as the construction of the mammoth Belo Monte hydroelectric dam and generous loans to the beef industry. Chopping down forest for pasture is the primary driver of deforestation.

The Amazon rainforest, which covers an area twice the size of India, acts as a buffer against climate change by absorbing large amounts of carbon dioxide. It’s also the most biodiverse forest in the world, and the home of tribes that have lived in the forest for thousands of years, some of them living in isolation.

“If da Silva wants to decrease forest destruction by 2023, he must have zero tolerance for environmental crime from Day One of his administration. That includes holding accountable those who sabotaged environmental governance in the country while in office over the past four years,” said Marcio Astrini, executive secretary of the Climate Observatory.

Source: Voice of America

November 30, 2022

This HIV Prevention Drug Could Change the Game

the drug, has not officially announced what it will cost in low- and middle-income countries, but it is expected to be much lower. Some aid groups have indicated that ViiV will offer the drug at $250 per year.

“The problem is that actually that won’t be really affordable for countries who need to roll it out and scale up,” said Jessica Burry, a pharmacist with humanitarian group Doctors without Borders.

PrEP pills cost about $54 per year, Warren said.

“The hope is that early in 2023, we can see a price point that is much closer to that 54 [dollars] than to the 250 [dollars],” he said. “Hopefully, in the $100 range per year.”

ViiV said it is working with the U.N.-backed Medicines Patent Pool to allow generic manufacturers to produce cabotegravir at a lower price for low- and middle-income countries.

ViiV said cabotegravir is more complicated to manufacture than most HIV drugs. No generic manufacturers have been selected yet. Once they are, it will take about three to five years before a generic version is on the market.

The company has filed for regulatory approval in 11 countries so far. Burry says there should be more.

“If they’re going to be the only supplier for the next four or five years until generics are available, then they really need to step up to the plate and actually file, register and get that drug available,” she said.

Demand for the drug is unclear. PrEP pills have been slow to catch on.

About 845,000 people in more than 50 countries took them in 2020, but the United Nations was aiming for 3 million by that time.

“We don’t have a ton of PrEP users, so if you’re ViiV, you’re looking at a very small market,” Warren said.

Warren said providers and advocates need to help grow that market. They need to do a better job connecting people at risk with programs that offer PrEP, he added.

“Some of the early PrEP programs began with us thinking that if you just bought the product, people would magically show up,” he said.

Warren hopes to change that as part of a coalition that includes ViiV, the Bill and Melinda Gates Foundation, the World Health Organization and others.

“There’s a huge effort in this coalition to bring in civil society from day one, and the communities that this product is meant to help and support,” he said.

The slow uptake means PrEP has not yet shown that it can make much of a real-world impact, Warren noted. He hopes to see research programs launch next year to find the best ways to reach the communities most at risk and lower infection rates.

“If we can’t show that in the next three years, then we don’t necessarily need all these generic manufacturers, because there will not be a market for this product,” he said.

Source: Voice of America

November 30, 2022

Malawi Launches Africa’s First Children’s Malaria Vaccine

Malawi and the World Health Organization are rolling out a new malaria vaccine for young children that backers say will reduce deaths from the mosquito-borne disease.

The RTSS vaccine was pilot tested on more than one million children in Ghana, Kenya and Malawi and recommended a year ago by the WHO. Despite a low effectiveness rate of 30%, the vaccine has raised hopes that some of the more than 400,000 people who die annually from malaria can be saved.

Malaria remains a huge public health problem in Malawi, with about one third of its 20 million people getting infected each year.

According to the ministry of health, the disease kills five Malawians every day, most of them children under the age of five or pregnant women who were not presented early enough for care.

The health ministry says the first phase of the vaccination campaign will target 330,000 children, who were not reached during vaccine trials.

The vaccine, sold by GlaxoSmithKline as Mosquirix, is meant for children under the age of five and requires four doses.

“Malaria is major problem in children. They are the ones at highest risk of dying,” said Dr. Charles Mwansambo, Malawi’s secretary for health. “That’s why even when we were doing the earlier studies, we found that once we get maximum benefit, we should target this age group. The main reason is that they are the ones that are most likely to die from malaria.”

Last year, the government launched a nationwide anti-malaria initiative known as Zero Malaria Starts with Me, aimed at eliminating the disease by 2030.

Mwansambo said the vaccine is a key part of that initiative.

“It actually prevents about 33 percent of deaths. Meaning that if you add the 33 to those that we can prevent using insecticide treated nets, if will also add on those [we can] prevent by indoor residual spraying, it [can] add up to something significant that will end up eliminating malaria,” he said.

However, the Bill and Melinda Gates Foundation, backers of the vaccine, have raised concerns about whether the vaccine is worth the cost.

In July, the Associated Press quoted Philip Welkhoff, director of malaria programs for the Gates Foundation, as saying the foundation will no longer offer direct financial support for the vaccine, although it will fund an alliance backing the vaccine.

He said Mosquirix has much lower efficacy than the foundation would like and that the vaccine is relatively expensive and logistically challenging to deliver.

Dr. Neema Kimambo, a WHO representative in Malawi, said the malaria vaccine itself is not a silver bullet but part of a combination of all interventions to fight the disease.

“Where it [vaccination] was done, we have seen how it has reduced under-five deaths and we believe that as we expand now, we are definitely to save more lives of children under five,” she said.

Maziko Matemba, a health activist and community health ambassador in Malawi, said he hopes the malaria vaccine efficacy will improve as time goes by.

“I have an example with COVID-19. When we had AstraZeneca, the efficacy when it started — as you know it was also a new vaccine — it was less that certain percentage and people said no it was less than this. But over time, we found that the efficacy has gone up,” Matemba said. “So we are monitoring the launch of this new vaccine with keen interest.

“I know that other partners are saying the worthiness of investment is not worth it, but looking at the way we are coming from, Malawi in particular, this could be one of the tools to prevent malaria.”

Besides WHO, other partners supporting Malawi in the fight against malaria include USAID, UNICEF, the Global Fund to Fight AIDS, Tuberculosis and Malaria and a global health nonprofit organization, PATH.

Source: Voice of America

November 29, 2022

World Health Organization Updates Emergency Use Listing for Novavax Nuvaxovid COVID-19 Vaccine as a Primary Series in Adolescents and as a Booster in Adults

GAITHERSBURG, Md., Nov. 29, 2022 /PRNewswire/ — Novavax, Inc. (Nasdaq: NVAX), a biotechnology company dedicated to developing and commercializing next-generation vaccines for serious infectious diseases, today announced that the World Health Organization (WHO) has issued an updated Emergency Use Listing (EUL) for Nuvaxovid (NVX-CoV2373) COVID-19 vaccine for active immunization to prevent coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as a primary series of two doses in adolescents aged 12 through 17 and as a booster in adults aged 18 and older.

“Today’s updated Emergency Use Listing from the WHO allows us to offer our protein-based vaccine as a primary series to adolescents and as a booster for adults around the world,” said Stanley C. Erck, President and Chief Executive Officer, Novavax. “WHO member countries now have a vaccine option for these indications developed using an innovative approach to traditional technology that can also be stored in standard refrigeration, making it easy to transport.”

Primary Series in Adolescents
The updated EUL for Nuvaxovid as a primary series in adolescents aged 12 through 17 was based on data from the ongoing pediatric expansion of the Phase 3 PREVENT-19 trial of 2,232 adolescents aged 12 through 17 years across 75 sites in the U.S., to evaluate the safety and effectiveness of Nuvaxovid. In the pediatric expansion, Nuvaxovid achieved its primary effectiveness endpoint and demonstrated 80% clinical efficacy overall at a time when the Delta variant was the predominant circulating SARS-CoV-2 strain in the U.S.

Preliminary safety data from the pediatric expansion showed the vaccine to be generally well-tolerated. Serious and severe adverse events were low in number and balanced between vaccine and placebo groups, and not considered related to the vaccine. Local and systemic reactogenicity was generally lower than or similar to adults, after the first and second dose. The most common adverse reactions observed were injection site tenderness/pain, headache, myalgia, fatigue, and malaise. There was no increase in reactogenicity in younger (12 to <15 years old) adolescents compared to older (15 to <18 years old) adolescents. No new safety signal was observed through the placebo-controlled portion of the pediatric expansion.

Booster in Adults
The updated EUL for Nuvaxovid as a booster in adults aged 18 and older is supported by data from Novavax’ Phase 2 trial conducted in Australia, from a separate Phase 2 trial conducted in South Africa, and from the United Kingdom (U.K.)-sponsored COV-BOOST trial. As part of the Novavax Phase 2 trials, a single booster dose of Nuvaxovid was administered to healthy adult participants approximately six months after their primary two-dose vaccination series of Nuvaxovid. The third dose produced increased immune responses comparable to or exceeding levels associated with protection in Phase 3 clinical trials. In the COV-BOOST trial, Nuvaxovid induced a meaningful antibody response when used as a heterologous third booster dose.

In the Novavax-sponsored trials, following the booster, local and systemic reactions had a median duration of approximately two days. The incidence of Grade 3 or higher events remained relatively low. Safety reporting of reactogenicity events showed an increasing incidence across all three doses of Nuvaxovid, often seen with increased immunogenicity. Medically attended adverse events (AE), potentially immune-mediated medical conditions, and severe AEs occurred infrequently following the booster dose and were balanced between vaccine and placebo groups.

In the 12 through 17-year-old population, Novavax’ vaccine has been authorized in more than 10 markets including the U.S., the European Union (EU), and the U.K. The vaccine has also been authorized as a booster in the U.S., EU, Japan, Australia, New Zealand, and Switzerland, and a number of other countries have policy recommendations allowing use of the vaccine as a heterologous or homologous booster dose. Novavax’ vaccine is actively under review in other markets for both indications and has ongoing trials to further explore its efficacy and safety as a booster.

The WHO previously granted EUL for Nuvaxovid in adults aged 18 and older in December 2021.

Trade Name in the U.S.
The trade name Nuvaxovid has not yet been approved by the U.S. Food and Drug Administration (FDA).

Important Safety Information: WHO

Nuvaxovid is contraindicated in persons who have a hypersensitivity to the active substance, or to any of the excipients.
Events of anaphylaxis have been reported with administration of Nuvaxovid. Appropriate medical treatment and supervision should be available in case of an anaphylactic reaction following the administration of the vaccine. Close observation for at least 15 minutes is recommended and a second dose of the vaccine should not be given to those who have experienced anaphylaxis to the first dose of Nuvaxovid.
Anxiety-related reactions, including vasovagal reactions (syncope), hyperventilation, or stress‐related reactions may occur in association with vaccination as a psychogenic response to the needle injection. It is important that precautions are in place to avoid injury from fainting.
Vaccination should be postponed in individuals suffering from an acute severe febrile illness or acute infection. The presence of a minor infection and/or low-grade fever should not delay vaccination.
Nuvaxovid should be given with caution in individuals receiving anticoagulant therapy or those with thrombocytopenia or any coagulation disorder (such as haemophilia) because bleeding or bruising may occur following an intramuscular administration in these individuals.
The efficacy of Nuvaxovid may be lower in immunosuppressed individuals.
Administration of Nuvaxovid in pregnancy should only be considered when the potential benefits outweigh any potential risks for the mother and foetus.
The effects with Nuvaxovid may temporarily affect the ability to drive or use machines.
Individuals may not be fully protected until 7 days after their second dose. As with all vaccines, vaccination with Nuvaxovid may not protect all vaccine recipients.
The most frequent adverse reactions in clinical trials in individuals 12 years of age and older were headache, nausea or vomiting myalgia, arthralgia, injection site tenderness, injection site pain, fatigue, and malaise.

For more information on Nuvaxovid, including the Summary of Product Characteristics with Package Leaflet, adverse event reporting instructions, or to request additional information, please visit the following websites:

About Nuvaxovid (NVX-CoV2373)
Nuvaxovid (NVX-CoV2373) is a protein-based vaccine engineered from the genetic sequence of the first strain of SARS-CoV-2, the virus that causes COVID-19 disease. The vaccine was created using Novavax’ recombinant nanoparticle technology to generate antigen derived from the coronavirus spike (S) protein and is formulated with Novavax’ patented saponin-based Matrix-M adjuvant to enhance the immune response and stimulate high levels of neutralizing antibodies. Nuvaxovid contains purified protein antigen and can neither replicate, nor can it cause COVID-19.

Nuvaxovid is packaged as a ready-to-use liquid formulation in a vial containing ten doses. The vaccination regimen calls for two 0.5 ml doses (5 mcg antigen and 50 mcg Matrix-M adjuvant) given intramuscularly 21 days apart. The vaccine is stored at 2°- 8° Celsius, enabling the use of existing vaccine supply and cold chain channels. Use of the vaccine should be in accordance with official recommendations.

Novavax has established partnerships for the manufacture, commercialization, and distribution of Nuvaxovid worldwide. Existing authorizations leverage Novavax’ manufacturing partnership with Serum Institute of India, the world’s largest vaccine manufacturer by volume. They will later be supplemented with data from additional manufacturing sites throughout Novavax’ global supply chain.

About the Novavax COVID-19 vaccine (NVX-CoV2373) Phase 3 Trials
The Novavax COVID-19 vaccine (NVX-CoV2373) continues being evaluated in two pivotal Phase 3 trials.

PREVENT-19 (the PRE-fusion protein subunit Vaccine Efficacy Novavax Trial | COVID-19) is a 2:1 randomized, placebo-controlled, observer-blinded trial to evaluate the efficacy, safety and immunogenicity of the Novavax COVID-19 vaccine with Matrix-M adjuvant in 29,960 participants 18 years of age and over in 119 locations in the U.S. and Mexico. The primary endpoint for PREVENT-19 was the first occurrence of PCR-confirmed symptomatic (mild, moderate or severe) COVID-19 with onset at least seven days after the second dose in serologically negative (to SARS-CoV-2) adult participants at baseline. The statistical success criterion included a lower bound of 95% CI >30%. A secondary endpoint was the prevention of PCR-confirmed, symptomatic moderate or severe COVID-19. Both endpoints were assessed at least seven days after the second study vaccination in volunteers who had not been previously infected with SARS-CoV-2. In the trial, the Novavax COVID-19 vaccine achieved 90.4% efficacy overall. It was generally well-tolerated and elicited a robust antibody response after the second dose in both studies. Full results of the trial were published in the New England Journal of Medicine (NEJM).

The pediatric expansion of PREVENT-19 is a 2:1 randomized, placebo-controlled, observer-blinded trial to evaluate the safety, effectiveness, and efficacy of the Novavax COVID-19 vaccine with Matrix-M adjuvant in 2,247 adolescent participants 12 to 17 years of age in 73 locations in the U.S., compared with placebo. In the pediatric trial, the vaccine achieved its primary effectiveness endpoint (non-inferiority of the neutralizing antibody response compared to young adult participants 18 through 25 years of age from PREVENT-19) and demonstrated 80% efficacy overall at a time when the Delta variant of concern was the predominant circulating strain in the U.S. Additionally, immune responses were about two-to-three-fold higher in adolescents than in adults against all variants studied.

Additionally, a trial conducted in the U.K. with 14,039 participants aged 18 years and over was designed as a randomized, placebo-controlled, observer-blinded study and achieved overall efficacy of 89.7%. The primary endpoint was based on the first occurrence of PCR-confirmed symptomatic (mild, moderate, or severe) COVID-19 with onset at least seven days after the second study vaccination in serologically negative (to SARS-CoV-2) adult participants at baseline. Full results of the trial were published in NEJM.

About Matrix-M Adjuvant
Novavax’ patented saponin-based Matrix-M adjuvant has demonstrated a potent and well-tolerated effect by stimulating the entry of antigen-presenting cells into the injection site and enhancing antigen presentation in local lymph nodes, boosting immune response.

About Novavax
Novavax, Inc. (Nasdaq: NVAX) is a biotechnology company that promotes improved health globally through the discovery, development, and commercialization of innovative vaccines to prevent serious infectious diseases. The company’s proprietary recombinant technology platform harnesses the power and speed of genetic engineering to efficiently produce highly immunogenic nanoparticles designed to address urgent global health needs. The Novavax COVID-19 vaccine, has received authorization from multiple regulatory authorities globally, including the U.S. FDA, the European Commission, and the WHO. The vaccine is currently under review by multiple regulatory agencies worldwide, including for additional indications and populations such as adolescents and as a booster. In addition to its COVID-19 vaccine, Novavax is also currently evaluating its COVID-19-Influenza Combination (CIC) vaccine candidate in a Phase 1/2 clinical trial, its quadrivalent influenza investigational vaccine candidate, and an Omicron strain-based vaccine (NVX-CoV2515) as well as a bivalent format Omicron-based / original strain-based vaccine. These vaccine candidates incorporate Novavax’ proprietary saponin-based Matrix-M adjuvant to enhance the immune response and stimulate high levels of neutralizing antibodies.

For more information, visit www.novavax.com and connect with us on LinkedIn.

Forward-Looking Statements
Statements herein relating to the future of Novavax, its operating plans and prospects, its partnerships, the timing of clinical trial results, the ongoing development of NVX-CoV2373, NVX-CoV2515 and a bivalent Omicron-based / original strain based vaccine, the CIC investigational vaccine candidate, a quadrivalent influenza investigational vaccine candidate, the scope, timing and outcome of future regulatory filings and actions, including Novavax’ plans to supplement existing authorizations with data from the additional manufacturing sites in Novavax’ global supply chain, additional worldwide authorizations of NVX-CoV2373 for use in adults and adolescents, and as a booster, the potential impact and reach of Novavax and NVX-CoV2373 in addressing vaccine access, controlling the pandemic and protecting populations, the efficacy, safety, intended utilization, and expected administration of NVX-CoV2373, and the expected administration of NVX-CoV2373 are forward-looking statements. Novavax cautions that these forward-looking statements are subject to numerous risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. These risks and uncertainties include, without limitation, challenges satisfying, alone or together with partners, various safety, efficacy, and product characterization requirements, including those related to process qualification and assay validation, necessary to satisfy applicable regulatory authorities; difficulty obtaining scarce raw materials and supplies; resource constraints, including human capital and manufacturing capacity, on the ability of Novavax to pursue planned regulatory pathways; unanticipated challenges or delays in conducting clinical trials; challenges meeting contractual requirements under agreements with multiple commercial, governmental, and other entities; and those other risk factors identified in the “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” sections of Novavax’ Annual Report on Form 10-K for the year ended December 31, 2021 and subsequent Quarterly Reports on Form 10-Q, as filed with the Securities and Exchange Commission (SEC). We caution investors not to place considerable reliance on forward-looking statements contained in this press release. You are encouraged to read our filings with the SEC, available at www.sec.gov and www.novavax.com, for a discussion of these and other risks and uncertainties. The forward-looking statements in this press release speak only as of the date of this document, and we undertake no obligation to update or revise any of the statements. Our business is subject to substantial risks and uncertainties, including those referenced above. Investors, potential investors, and others should give careful consideration to these risks and uncertainties.

Contacts:
Investors
Erika Schultz | 240-268-2022
ir@novavax.com

Media
Ali Chartan or Giovanna Chandler | 202-709-5563
media@novavax.com

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November 29, 2022

EYES ON IRAN ART ACTIVATION FACES THE U.N. IN NEW YORK

AN EVENT MARKED THE OPENING FEATURING HILLARY RODHAM CLINTON, GISSOU NIA,SHEIDA SOLEIMANI, SHIRIN NESHAT with SPECIAL PERFORMANCE BY JON BATISTE

NEW YORK, Nov. 28, 2022 (GLOBE NEWSWIRE) — Iranian artists Sheida Soleimani, Aphrodite Désirée Navab, Z, Icy and Sot, Shirin Neshat, Mahvash Mostala, Sepideh Mehraban, and Shirin Towfiq, alongside artists Hank Willis Thomas and JR, activate New York’s FDR Four Freedoms State Park with a provocative multi-day and multi-media art installation facing the United Nations entitled Eyes on Iran, November 28, 2022 – January 1, 2023.

Timed for the U.N. initiative, 16 Days of Activism Against Gender-Based Violence, the installations are focused on the power of collective sight, with eyes facing the U.N., signifying the world’s eyes on Iran. ‘Eyes in the Sky’ flying billboards featuring artworks by Thomas and Mostala will fly on December 3 in New York City and on November 28 and 30 in Miami. An interactive installation by artist JR will take place on December 4. Eyes on Iran aims to amplify the mission of Woman, Life, Freedom, a campaign demanding that the Islamic Republic of Iran is removed from the Commission on the Status of Women.

The New York installation was unveiled at an event featuring former U.S. Secretary of State Hillary Rodham Clinton, Human Rights Lawyer and Director of the Strategic Litigation Project at the Atlantic Council Gissou Nia, artists Sheida Soleimani and Shirin Neshat, actor and singer Sepideh Moafi and more at FDR Four Freedoms State Park with a performance by Grammy award-winner Jon Batiste.

“We are calling on the world to take more action, starting at the United Nations. We must remove Iran from the U.N.’s Commission on the Status of Women. The fact that Iran is a member is a bitter irony,” said Clinton. “What we are seeing is a revolution led by young women who are just not willing to live with the loss of freedom being imposed upon them.”

November 28 is significant because it is the anniversary of the 1943 Tehran Conference where Allied leaders, Franklin D. Roosevelt, Winston Churchill and Joseph Stalin met in Tehran to coordinate the Allied military strategy and also stated a shared desire for the maintenance of the independence, sovereignty, and territorial integrity of Iran. Today, Woman, Life, Freedom shares the call for human rights for the people of Iran.

“The world’s eyes have been focused on the courage of Iranian citizens in their quest for freedom, in the face of increasingly grave danger,” said human rights activist Nazanin Afshin-Jam Mackay. “The Islamic Republic has censored them and attempted to blind the world to the potential of this movement. ‘Eyes on Iran’ is our response to their call for a free Iran.”

“When we say that we must keep our ‘Eyes on Iran,’ we mean that what is happening deserves not only our attention but our vision. In solidarity with the courageous Iranians who are risking their lives to express their human rights, many artists throughout the diaspora and beyond are bringing our vision to bear to ensure international audiences and institutions remain aware of what is happening in Iran, in their eyes and in their hearts, and feel moved to respond,” says artist Shirin Neshat.

An interactive installation by artist JR will take place on December 4 at FDR Four Freedoms State Park. Eyes on Iran aims to amplify the mission of Woman, Life, Freedom, a campaign demanding that the Islamic Republic of Iran is removed from the Commission on the Status of Women. Additional artists featured online including Emily Elise, Mahdis Nikou, Priscillia Kounkou Hoveydam, Ernesto Yerena, Hourdad, Golnar Adili, and Anonymous Artists.

In October, the campaign published a two-page ad in The New York Times with a petition signed by women leaders from more than 14 countries, including Clinton, demanding the U.N. Member States remove the Islamic Republic of Iran from the Commission on the Status of Women. Within days, Prime Minister Jacinda Ardern of New Zealand, Canadian Deputy Prime Minister Chrystia Freeland, and Foreign Affairs Minister Melanie Joly, along with nearly 100,000 others, signed the petition.

The Woman, Life, Freedom campaign is a partnership between artist collective For Freedoms, a coalition of Iranian women leaders and Vital Voices Global Partnership, a non-profit elevating women leaders.

Key Links:

Press Images

Woman Life Freedom Website

Press Release: Open Letter Calling for the Immediate Expulsion of the Islamic Republic of Iran from the UN Commission on the Status of Women

About Our Partners:

For Freedoms is an artist collective that centers art and creativity as a catalyst for transformative connection and collective liberation. By wielding the power of art, we aim to deepen and expand our capacity to interrogate what is and imagine what could be. Together, we seek infinite expansion.
www.forfreedoms.com

Vital Voices Global Partnership celebrates 25 years of directly investing in more than 20,000 women leaders across 184 countries since 1997. Driven by the universal truth that women are the key to progress in their communities and nations cannot move forward without women in leadership positions, Vital Voices has provided early support for leaders who went on to become Nobel Peace Prize Laureates, U.S. Youth Poet Laureates, prime ministers, award-winning innovators, pioneering human rights defenders, and breakthrough social entrepreneurs.
www.vitalvoices.org

Four Freedoms Park Conservancy (FFPC), founded in 2011, operates under a Friends Agreement with New York State Parks to produce and curate public programs at Franklin D. Roosevelt Four Freedoms State Park. The park, designed by American modernist architect Louis Kahn, is among the greatest architectural masterpieces in New York City. By leveraging this spectacular architecture and the unique location of the park, the Conservancy produces events, installations,public art, and partners with local organizations that, together, serve a singular purpose: igniting the conversation around the Four Freedoms and the legacy of President Franklin D. Roosevelt.
www.fdrfourfreedomspark.org

The New York State Office of Parks, Recreation and Historic Preservation oversees more than 250 parks, historic sites, recreational trails, golf courses, boat launches and more, which are visited by more than 78 million people annually. For more information on any of these recreation areas, visit www.parks.ny.gov, download the free NY State Parks Explorer mobile app or call 518.474.0456. Also, connect on Facebook, Instagram and Twitter.

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Sarah Brown McLeod
DEPARTMENT PR
sarah@department-pr.com

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